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  1. #461
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    Default Re: TRUVADA: Why are we ALL not taking this???!!!!

    BBC News report:

    'Give HIV drugs to healthy gay men:Healthy gay men should be offered daily HIV drugs to prevent infections, say UK Medical Research Council and Public Health England scientists.'

    http://www.bbc.co.uk/news/health-31601042



  2. #462
    Platinum Poster natina's Avatar
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    Default Re: TRUVADA: Why are we ALL not taking this???!!!!

    Pill taken before, after sex may prevent HIV


    An HIV prevention pill, called Truvada, taken by gay men before and after sex reduced the risk of virus transmission by 86 percent, according to the results of a clinical trial

    An HIV prevention pill taken by gay men before and after sex reduced the risk of virus transmission by 86 percent, according to the results of a clinical trial released Tuesday.
    Truvada contains HIV treatment drugs tenofovir and emtricitabine, and is made by Gilead Sciences in California. In the study Truvada was taken up to one day before sex and the two days after.
    The study, led by the French National HIV research agency ANRS, was presented at the Conference on Retroviruses and Opportunistic Infections (CROI) in Seattle.
    Until now, Truvada as a preventive measure has been prescribed only as a once-a-day regimen, not one that could be effective if taken around the time of sex.
    While the latest evidence on the technique known as pre-exposure prophylaxis, or PrEP, is not enough to change guidelines, it was welcomed as a novel approach to HIV prevention.
    The study "provides the first evidence that an event-driven regimen is effective among high-risk MSM (men who have sex with men) with frequent sex," said Jonathan Mermin, director of the US Centers for Disease Control and Prevention's National Center for HIV/AIDS.
    Truvada was approved in 2012 by the US Food and Drug Administration as the first daily pill to help prevent human immunodeficiency virus in some high-risk groups.
    - Three pills -
    The latest trial, called IPERGAY, was a randomized, placebo-controlled study that began in February 2012 and was halted in October 2014 when an independent data safety review board found it had a high rate of effectiveness.
    A total of 400 participants were enrolled.
    Those in the trial were considered to be at high-risk of acquiring HIV because they were having sex an average of 10 times per month, and with eight partners every two months.
    Some participants took a placebo, while others took Truvada two to 24 hours before sex, then again 24 and 48 hours later.
    The research team "reported that PrEP reduced HIV risk among the MSM who were prescribed this regimen by an average of 86 percent," according to a statement.
    Previous research on Truvada to prevent HIV has found that those who took it regularly could lower their risk of getting HIV by as much as 92 percent.
    Most of the men in the study were taking Truvada four days a week, and it remains to be seen if the regimen would be as effective among men having sex less frequently
    Mermin cautioned that it remains unknown whether Truvada taken only in the hours before sex and the two days afterward could work in heterosexual men and women, or injection drug users, or outside a tightly controlled trial.
    "CDC continues to recommend only daily use of PrEP, as approved by the FDA," Mermin said.
    "Daily, oral PrEP is recommended by CDC as an option for men who have sex with men, heterosexual men and women, and injection drug users."

    - More PrEP study -
    A second study released at CROI by the UK Medical Research Council found that daily oral PrEP using Truvada reduced risk of HIV transmission among gay men by 86 percent.
    A third study examined the use of a daily pill to prevent HIV among heterosexual couples in which one person is HIV positive and the other is not.
    Led by the University of Washington, the trial underway in Kenya and Uganda is probing the efficacy of PrEP as a transitional strategy, to protect one partner from HIV while the HIV-positive partner gets his or her viral load under control through antiretroviral medication.
    "Preliminary results show that this dual strategy reduced the risk of HIV infection by 96 percent," Mermin said.
    "These findings together provide encouraging additional evidence of the power of PrEP to reduce the risk of HIV infection."
    Since PrEP does not work all the time, nor does it prevent sexually transmitted infections like syphilis and gonorrhea, health authorities say people should continue to use condoms regularly.
    Common side effects of Truvada include diarrhea, nausea, abdominal pain, headache and weight loss

    http://www.msn.com/en-us/health/medi...hiv/ar-BBhVBug



  3. #463
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    Default Re: TRUVADA: Why are we ALL not taking this???!!!!




  4. #464
    Professional Poster lifeisfiction's Avatar
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    Default Re: TRUVADA: Why are we ALL not taking this???!!!!

    Interesting articles. I wonder how many were using Truvada without condoms. Some people still use condoms while on Truvada. This gets more interesting each time. I really want to know the numbers for people who rely on Truvada alone as their main means of protection.



  5. #465
    Veteran Poster Westheangelino's Avatar
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    Default Re: TRUVADA: Why are we ALL not taking this???!!!!

    ^ Two months in with no side effects!


    3 out of 3 members liked this post.

  6. #466
    Silver Poster fred41's Avatar
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    Default Re: TRUVADA: Why are we ALL not taking this???!!!!

    I actually think once price comes down a bit more, lots of people are going to be on this...but I think right now Gilead is making more money from their Hep C drugs...so they are not actively marketing this drug :
    http://www.fiercepharma.com/story/he...ing/2015-02-18

    ...Best of luck with the drug trial Wes !!



  7. #467
    5 Star Poster sukumvit boy's Avatar
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    Default Re: TRUVADA: Why are we ALL not taking this???!!!!

    Here's an update on a new Truvada type drug for those interested .
    By the way ,sorry to hear about poster "Westheangelino" ,heard he past away RIP.
    https://science.sciencemag.org/content/368/6493/807



  8. #468
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    Default Re: TRUVADA: Why are we ALL not taking this???!!!!

    Quote Originally Posted by lifeisfiction View Post
    Interesting articles. I wonder how many were using Truvada without condoms. Some people still use condoms while on Truvada. This gets more interesting each time. I really want to know the numbers for people who rely on Truvada alone as their main means of protection.
    In my experience, some PrEP users are pretty cavalier about condom use and feel comfortable bare-backing.



  9. #469
    Senior Member Silver Poster MrFanti's Avatar
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    Default Re: TRUVADA: Why are we ALL not taking this???!!!!

    Quote Originally Posted by sukumvit boy View Post
    Here's an update on a new Truvada type drug for those interested .
    By the way ,sorry to hear about poster "Westheangelino" ,heard he past away RIP.
    https://science.sciencemag.org/content/368/6493/807
    Yes he passed and he was right about a number things - great to see that he stood his ground against all the hostility that he received here for just trying to help us.


    2 out of 2 members liked this post.
    "I am, a SIGMA Male...

  10. #470
    Senior Member Junior Poster
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    Default Re: TRUVADA: Why are we ALL not taking this???!!!!

    Quote Originally Posted by MrFanti View Post
    Yes he passed and he was right about a number things - great to see that he stood his ground against all the hostility that he received here for just trying to help us.
    Well said. Lots of comments in this thread are cringy with age.



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