FDA review favors first drug for HIV prevention

[tsbrenda]

FDA review favors first drug for HIV prevention

A pill that has long been used to treat HIV has moved one step closer to becoming the first drug approved to prevent healthy people from becoming infected with the virus that causes AIDS.

The Food and Drug Administration said Tuesday that Gilead Sciences' Truvada appears to be safe and effective for HIV prevention. It concluded that taking the pill daily could spare patients "infection with a serious and life-threatening illness that requires lifelong treatment."

On Thursday a panel of FDA advisers will consider the review when it votes on whether Truvada should be approved as a preventative treatment for people who are at high risk of contracting HIV through sexual intercourse. The FDA is not required to follow the advice of its panels, but it usually does.

An estimated 1.2 million Americans have HIV, which attacks the immune system and, unless treated with antiviral drugs, develops into AIDS, a fatal condition in which the body cannot fight off infections. If Truvada is approved, it would be a major breakthrough in the 30-year campaign against the AIDS epidemic. There have been no other drugs proven to prevent HIV and a vaccine is believed to be decades away.

Gilead Sciences Inc., based in Foster City, Calif., has marketed Truvada since 2004 as a treatment for people who are infected with the virus. The medication is a combination of two older HIV drugs, Emtriva and Viread. Doctors usually prescribe the medications as part of a drug cocktail that makes it harder for the virus to reproduce. Patients with low viral levels have reduced symptoms and are far less likely to develop AIDS
Researchers first reported that Truvada could prevent people from contracting HIV in 2010. A three-year study found that daily doses cut the risk of infection in healthy gay and bisexual men by 44 percent, when accompanied by condoms and counseling. Another study found that Truvada reduced infection by 75 percent in heterosexual couples in which one partner was infected with HIV and the other was not.

Because Truvada is already on the market to manage HIV, some doctors already prescribe it as a preventive measure. But FDA approval would allow the drugmaker Gilead Sciences to formally market its drug for that use.

http://www.msnbc.msn.com/id/47345265/ns/health-aids/

[Steve-Oh]

Cool Story Bren.

Does this mean it's ok to Bareback Like a Maniac?

[Dino Velvet]

Does this mean it's ok to Bareback Like a Maniac?

That was the first thing that popped up in my mind. Condom companies will go bankrupt. Get the snip(unless your gal can't get preggars) then go for broke.:fuckin:

[nina_lisa]

Cool Story Bren.

Does this mean it's ok to Bareback Like a Maniac?

Well it was also my thought, but if you read the article you will find it only cut the risk by 44% or 77% and not by 100%.

[Marty Mcfly]

Don't have unprotected Anal sex or shoot up and you will not have to worry about HIV!

[Quiet Reflections]

Don't have unprotected Anal sex or shoot up and you will not have to worry about HIV!
if only it was that simple. There are plenty of people that don't have anal sex that have hiv/aids. A friend of mine got Hiv in a bar fight and has never done drugs a day in his life.

[jimbo1974]

A friend of mine got Hiv in a bar fight and has never done drugs a day in his life.

How did this happen ?

[Wendy Summers]

How did this happen ?

I'll take Blood exposure in open wound for $100

[tsbrenda]

you can still get herpes,warts,viruses,hepatitis and antibiotic resistant venereal diseases



Antibiotic-Resistant Gonorrhea


http://www.cdc.gov/std/gonorrhea/arg/

Drug-resistant syphilis is spreading

Study finds mutant strain no longer responds to azithromycin


http://www.msnbc.msn.com/id/5387438/ns/health-sexual_health/t/drug-resistant-syphilis-spreading/


antibiotic resistant chlamydia
http://jid.oxfordjournals.org/content/181/4/1421.full.pdf

[lifeisfiction]

Does this mean it's ok to Bareback Like a Maniac?

Only when they have a cure. That also includes a cure for herpes and hepatitis. Then yes it will be bareback mania. We will have an all out HA celebration orgy the day that happens.

[Jarhead1968]

if only it was that simple. There are plenty of people that don't have anal sex that have hiv/aids. A friend of mine got Hiv in a bar fight and has never done drugs a day in his life.
anytime you have someone with HIV (this is in his or her blood) THAT contacts someone else's blood, you have a very high probability of spread. That being said, anal sex is conducive to spreading the HIV virus because of the friability of the anal mucosa. Oral sex is very hard to spread HIV because of the enzymes in the saliva.
I'm not a physician but you should check with one to be sure.

Jarhead

[Quiet Reflections]

How did this happen ?
Wendy would be correct. It was about 10 years ago and my friends and I were out drinking and we see a few other guys we know from around that are also drunk and talking shit. Well us being in our early 20's and invincible we decided to shut them up. A few chairs, broken bottles and glasses later we were all cut up and bloody. Not much happened after that but about a year later my friend (still a non drug using virgin) gets in a car accident. while at the hosptial he finds out he is Hiv positive. The only blood/ fluid exchange he could think of was the bar fight and after a bit of research. He found out one of the guys we had been in a fight with had also given his girlfriend HIV and later killed himself upon finding out he had it. He wasn't a drug user or a bad guy either just a bit to promiscuous.

[Jarhead1968]

Well it was also my thought, but if you read the article you will find it only cut the risk by 44% or 77% and not by 100%.
Given the absolute numbers, that is a hell of a lot better than 0 %, yet don't be complacent.

Jarhead

[Quiet Reflections]

anytime you have someone with HIV (this is in his or her blood) THAT contacts someone else's blood, you have a very high probability of spread. That being said, anal sex is conducive to spreading the HIV virus because of the friability of the anal mucosa. Oral sex is very hard to spread HIV because of the enzymes in the saliva.
I'm not a physician but you should check with one to be sure.

Jarhead
OK what does that have to do with what I said? We are both correct. You can get it from anal sex but there are plenty of people in this world that don't have anal sex and are HIV positive. Go to any support group for women with HIV and tell them that they all got it from drugs and anal sex and see if you don't limp out of those doors. HIV has touched my life in a few different ways I do know a bit about it. I'm lucky enough to have gotten out of that bar fight uninfected but my pal was not so lucky.

[tsbrenda]

DO NOT LOOK AT THIS WHILE EATING!

anal warts - Google Search (http://www.google.com/search?hl=en&rlz=1G1LENN_ENUS480&=&q=anal+warts&um=1&ie=UTF-8&tbm=isch&source=og&sa=N&tab=wi&ei=RTyvT7nyFoemiQLY4NCKBA&biw=1366&bih=576&sei=SDyvT6WDNMaLiAKQg6nrAw)


you can still get herpes,warts,viruses,hepatitis and antibiotic resistant venereal diseases



Antibiotic-Resistant Gonorrhea


http://www.cdc.gov/std/gonorrhea/arg/

Drug-resistant syphilis is spreading

Study finds mutant strain no longer responds to azithromycin


http://www.msnbc.msn.com/id/5387438/ns/health-sexual_health/t/drug-resistant-syphilis-spreading/


antibiotic resistant chlamydia

http://jid.oxfordjournals.org/content/181/4/1421.full.pdf

[natina]

Can oral sex really give you cancer?
http://vitals.msnbc.msn.com/_news/2012/03/23/10832041-can-oral-sex-really-give-you-cancer?lite

Oral Sex May Cause More Throat Cancer Than Smoking in Men, Researchers Say

http://www.bloomberg.com/news/2011-10-03/oral-sex-may-cause-virus-linked-throat-cancer-in-men-study.html


Reports of an increase in head and neck cancers that are caused by human papillomavirus, or HPV, have led some to propose that changes in sexual behavior, specifically an increase in oral sex, are responsible.
But experts say such conclusions may be premature, or at least overstated, and are leading to unnecessary worry.
While oral sex may be a risk factor (http://www.livescience.com/12933-teens-view-oral-sex-safer-brings-cancer-risks.html)for some types of head and neck cancer, the link is, at this point, speculative, experts say. Moreover, there are many other elements that play a role in whether a person develops cancer, including the strength of the immune system, said Sara Rosenquist, a psychologist and sex therapist in North Carolina.
In general, there is no need for individuals in monogamous relationships to restrict their sexual activities if the pair is in good health, Rosenquist said.
Rosenquist recently wrote an article in the Journal of Sexual Medicine to dispel myths about oral sex and cancer.
First, Rosenquist notes cases of head and neck cancer (http://www.cancer.gov/cancertopics/factsheet/Sites-Types/head-and-neck)are not increasing. As a group, cases of this cancer have actually declined in the United States over the past 25 years. However, there has been in increase in the proportion of head and neck cancers caused by HPV, primarily among younger individuals.
HPV is thought to be, for the most part, sexually transmitted. The viruses cause almost all cases of cervical cancer (http://www.myhealthnewsdaily.com/1860-home-hpv-testing-cervical-cancer-screening.html), and can cause genital warts and anal cancer. The link between HPV and oral cancers is less clear.
Oral sex has been linked with an increased risk of acquiring an HPV infection in the mouth, and with an increased risk of developing oral cancers that are caused by HPV. But sex in general has also been linked with these risks.
A study published this year in the Journal of the American Medical Association (JAMA) found people who reported engaging in oral sex were twice as likely to have an oral HPV infection (http://www.myhealthnewsdaily.com/2161-oral-hpv-infection-united-states.html)as those who did not engage in oral sex. But people who reported having sex of any kind were eight times more likely to have an oral HPV infection than those who had not had sex.
"There are no data to directly support a link between changes in sexual behavior and increased incidence of HPV-associated cancer, because the data do not exist," Dr. Maura Gillison, chair of cancer research at Ohio State University who has studied HPV, told MyHealthNewsDaily in an email.
An HPV infection becomes concerning if it persists in the body for a long time, as persistent HPV infections are more likely to cause cancer, Rosenquist said. And persistent infections occur when the body's immune system can't clear the virus. So any factors that would compromise the immune system function may increase cancer risk.
The more sexual partners (http://www.livescience.com/7038-men-report-sex-partners-women.html)a person has, the more swamped their immune system becomes, Rosenquist said. So if any sexual behavior change is responsible for the uptick in oral cancers caused by HPV, it's an increase in promiscuity, not oral sex, Rosenquist said.
The JAMA study found that among teens and adults who'd had 20 or more sexual partners in their lifetimes, one in five had an oral HPV infection. Another study found that people who had performed oral sex on six or more partners in their lifetime had an eightfold increased risk of cancers of the mouth or throat.
If you are in a monogamous relationship and have had fewer than six sexual partners in your lifetime, chances are "that you and your partner will be swapping HPV back and forth, with infections waxing and waning over your lifetime," Rosenquist said.
If you are able to clear HPV, but your partner is not, you may both be at risk of a persistent infection, Rosenquist said. A 2006 study found that the presence of a persistent HPV infection in one partner in a relationship increased the risk of a persistent infection in the other partner tenfold.
HPV should not be a concern for monogamous couples if there is no sex outside the relationship and they do not encounter factors that could comprise the immune system, Rosenquist said.
"Sexually active adults are more likely to benefit from healthy lifestyles that promote good immune functioning coupled with regular medical checkups aimed at early detection and treatment," Rosenquist said.
Rosenquist also advises couples to stop worrying, as worry and stress may also reduce immune system strength.

[Helvis2012]

This could be huge.

[top4bigbutt]

Shit gate news, but we still sould protect anaconda from "others" bugs...
Again this can be so good

[buttslinger]

I heard it cost 900 bucks a month.

[natina]

who is taking the drug here?

[natina]

The AIDS epidemic: Beginning of the end?

http://www.hungangels.com/vboard/showthread.php?t=68833